1. Raindrops Keep Falling on My Head
Air date: 2005-09-25 · 60 min
As Meredith and Cristina discuss their relationship woes at the Emerald City Bar, their session of lamenting is interrupted when Joe, the bartender, collapses. And as Chief Webber recovers from brain surgery, he appoints one surgeon as interim chief -- much to the dismay of another surgeon -- and he assigns George to report back with hospital gossip. While a devastated Meredith learns more about Derek and Addison's relationship, a confused Cristina tries to make decisions about her connection with Dr. Burke.
Open episode 1 ↗2. Enough Is Enough (No More Tears)
Air date: 2005-10-02 · 60 min
McDreamy wants to get back with Meredith. Addison wants to get back with McDreamy. Meredith just wants to keep it professional -- with both of them.
Open episode 2 ↗3. Make Me Lose Control
Air date: 2005-10-09 · 60 min
Some very deep secrets are made painfully public when Meredith's mother, who suffers from Alzheimer's disease, is brought to Seattle Grace for a surgical procedure. Meanwhile, some frightening news about Cristina's health is brought out into the open.
Open episode 3 ↗4. Deny, Deny, Deny
Air date: 2005-10-16 · 60 min
As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor any. And Meredith's mother, Dr. Ellis Grey, has the hospital staff running in circles. Jeremiah, a cystic fibrosis patient, could benefit from Dr. Addison Shepherd's medical knowledge, but her involvement in his surgery could delay her highly anticipated departure from Seattle Grace Hospital, leaving Meredith and Derek's relationship hanging in the balance.
Open episode 4 ↗5. Bring the Pain
Air date: 2005-10-23 · 60 min
Meredith and Dr. Shepherd have to use more than medicine when a young woman's traditionalist, religious father forbids her to have a life-saving operation. Meanwhile, George and Alex are forced to perform surgery under less than ideal conditions in an attempt to save a patient's life, and its decision time for Derek and the two women in his life.
Open episode 5 ↗6. Into You Like a Train
Air date: 2005-10-30 · 60 min
A massive train crash causes two victims to be impaled on the same pole. Izzie chooses between friendship and advancing her career.
Open episode 6 ↗7. Something to Talk About
Air date: 2005-11-06 · 60 min
Gossip is all the rage at Seattle Grace with Meredith feeling the brunt of it as a pregnant man comes into SGH and a heart spontaneously combusts!
Open episode 7 ↗8. Let It Be
Air date: 2005-11-13 · 60 min
McDreamy and Addison clash over their friend's request for radical surgery, while Meredith's elderly patients restore her belief in true love.
Open episode 8 ↗9. Thanks for the Memories
Air date: 2005-11-20 · 60 min
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner at Meredith's -- but it remains to be seen who among the invited guests will actually show up. Meanwhile, George endures the O'Malley tradition of hunting turkeys with his less-than-sophisticated family, and Meredith treats a patient who's been in a vegetative state for 16 years.
Open episode 9 ↗10. Much Too Much
Air date: 2005-11-27 · 60 min
Meredith's one night stand causes complications when he shows up at the hospital with an embarrassing problem. Meanwhile, Burke tries to push Cristina toward the next step, and Alex's problems affect his performance.
Open episode 10 ↗11. Owner of a Lonely Heart
Air date: 2005-12-04 · 60 min
Cristina has little sympathy for Constance Ferguson, a prison inmate who jeopardizes her health just to get out of solitary confinement.
Open episode 11 ↗12. Grandma Got Run Over by a Reindeer
Air date: 2005-12-11 · 60 min
A boy needs a heart transplant but doesn't want it, and an argument over his treatment exposes philosophical differences between Burke and Cristina.
Open episode 12 ↗13. Begin the Begin
Air date: 2006-01-15 · 60 min
Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient who's awaiting a heart transplant.
Open episode 13 ↗14. Tell Me Sweet Little Lies
Air date: 2006-01-22 · 60 min
Meredith must choose between her dog and her roommates. Meanwhile, George deals with an elderly patient who has outstayed her welcome, Bailey's pregnancy has complications, Alex gets his exam results, and Richard has a strike on his hands.
Open episode 14 ↗15. Break on Through
Air date: 2006-01-29 · 60 min
The nurses are striking, and George refuses to cross the picket line. The interns are surprised by Bailey's seemingly immature replacement, Izzie connects with a pregnant girl, and an elderly woman's plight pushes Meredith to the limit.
Open episode 15 ↗16. It's the End of the World
Air date: 2006-02-05 · 60 min
Meredith's fears that she is in for a bad day are realized when a medical case arrives at SGH that threatens the lives of everyone in the O.R.
Open episode 16 ↗17. As We Know it
Air date: 2006-02-12 · 60 min
Despite the best efforts of the Seattle Grace staff, the code black situation escalates.
Open episode 17 ↗18. Yesterday
Air date: 2006-02-19 · 60 min
Meredith and Burke treat a patient who probably won't survive surgery and the patient asks Meredith to videotape him venting.
Open episode 18 ↗19. What Have I Done to Deserve This?
Air date: 2006-02-26 · 60 min
No one knows what transpired between George and Meredith but George and Meredith -- and they aren't talking.
Open episode 19 ↗20. Band-Aid Covers the Bullet Hole
Air date: 2006-03-12 · 60 min
It becomes a bad day for Cristina when Bailey instructs her to take care of her baby.
Open episode 20 ↗21. Superstition
Air date: 2006-03-19 · 60 min
After four deaths in the morning, every doctors' personal superstitions and rituals come into focus.
Open episode 21 ↗22. The Name of the Game
Air date: 2006-04-02 · 60 min
George begins to overstay his welcome at Burke's apartment, Meredith learns a secret about her father, and Alex gets a lesson in bedside manners.
Open episode 22 ↗23. Blues for Sister Someone
Air date: 2006-04-30 · 60 min
Derek and Addison aren't having the best sex, something Meredith learns of by accident, just before Finn asks her out.
Open episode 23 ↗24. Damage Case
Air date: 2006-05-07 · 60 min
Derek is mad at Meredith; George is living back in the house, though still not talking to Meredith; and Cristina begins the day on a rush.
Open episode 24 ↗25. 17 Seconds
Air date: 2006-05-14 · 60 min
A shooting at a nearby restaurant bombards the hospital with plenty of gunshot victims -- and one intended victim that didn't get shot.
Open episode 25 ↗26. Deterioration of the Fight or Flight Response
Air date: 2006-05-15 · 60 min
Burke has been shot and Izzie has just cut Denny's LVAD wire. George, Meredith, and Cristina all wind up helping Izzie keep Denny alive.
Open episode 26 ↗27. Losing My Religion
Air date: 2006-05-15 · 60 min
Denny proposes to Izzie after receiving his new heart and Burke experiences hand tremors after awakening from his surgery. Meanwhile, the interns plan the prom for the Chief's niece while awaiting their fateful meeting with the Chief; George and Callie have a heart-to-heart about his feelings for her; and Meredith and Derek must make a decision about Doc. Mer also must decide between Derek and Finn.
Open episode 27 ↗