1. Aloha, Everyone
Air date: 2025-11-03 · 30 min
Alex tries to hold on to her peaceful vacation vibes. Joyce faces a design crisis in the birthing center. Matt and Serena reassess their working relationship.
Open episode 1 ↗St. Denis Medical
Season 2.
18 episodes in the catalogue. Explore the stories and air dates, then choose an episode to open FRAME’s player.
2. Mama Bear Activated
Air date: 2025-11-03 · 30 min
After Bruce is attacked at the hospital, Matt helps him deal with the aftermath. Alex motivates Joyce to amp up security, while Ron and Serena debate who is more qualified to defend themselves.
Open episode 2 ↗3. Get Me in the Pod, Brother
Air date: 2025-11-10 · 30 min
Alex and Ron spar over the wisdom of open communication. Joyce brings in a body scanner that proves overly distracting.
Open episode 3 ↗4. Two Docs, One Conf
Air date: 2025-11-17 · 30 min
Ron and Bruce butt heads at a medical conference. Joyce tries to show her nurses some love for Nurse Appreciation Week.
Open episode 4 ↗5. A Strong Cup of Coffee
Air date: 2025-11-24 · 30 min
Alex is eager to impress her old charge nurse, Pam, who comes back to St. Denis. Serena and Matt try to solve a patient's mystery illness.
Open episode 5 ↗6. I Left a Woman on the Table
Air date: 2025-12-01 · 30 min
Matt struggles to deal with a patient from his past. Bruce tries to rekindle romance with a former flame. Joyce treats patients to cover a nursing shortage.
Open episode 6 ↗7. No Wonder His Kidney Wants Out
Air date: 2025-12-08 · 30 min
Ron and Alex react very differently to a seemingly selfless patient. Joyce runs into an old flame. Matt helps Bruce find a new best friend.
Open episode 7 ↗8. A Waste of Time and Marble
Air date: 2025-12-15 · 30 min
With the threat of a nurse walkout, Alex is caught between her colleagues and Joyce. Ron and Bruce go above and beyond to help an unexpected patient.
Open episode 8 ↗9. You're in His Bubble Space
Air date: 2026-01-05 · 30 min
Ron and Matt try to convince a child to get his shot. Alex helps Joyce with wedding planning. Bruce and Serena butt heads over Matt.
Open episode 9 ↗10. This Is From Joyce
Air date: 2026-01-12 · 30 min
Serena and Alex work a "Botox and Bubbly" party. Joyce enlists Matt's help with a personal issue. Bruce introduces Ron to the world of memecoins.
Open episode 10 ↗11. This Isn't Bingo
Air date: 2026-01-26 · 30 min
Alex hosts a senior health fair; Bruce resuscitates a patient with a DNR; Ron competes with Matt over a patient's homemade fudge.
Open episode 11 ↗12. Nod and Agree
Air date: 2026-02-02 · 30 min
Ron tries to wrap up a perfect visit from his son, Michael. Alex questions Val's return from jury duty. Bruce feels iced out of a juicy business opportunity.
Open episode 12 ↗13. A New Best Friend
Air date: 2026-03-02 · 30 min
Alex's husband gets treated by Bruce; Joyce goes on an accidental journey; Ron's shoes squeak.
Open episode 13 ↗14. Happy Birthday, Matty
Air date: 2026-03-09 · 30 min
Matt's first birthday party gets crashed by a rival; Joyce decides to "get back out there."
Open episode 14 ↗15. Everyone Loves Portland General
Air date: 2026-03-16 · 30 min
Bruce considers a new chapter in his career; Serena uses a baby to get out of work; Matt helps Ron log onto his computer.
Open episode 15 ↗16. Experience with Human Babies
Air date: 2026-03-23 · 30 min
Alex helps Joyce hire a midwife; Bruce joins Matt for an ambulance ride along. Serena and Ron butt heads over a pen.
Open episode 16 ↗17. Here a Righteous Woman Comes
Air date: 2026-03-30 · 30 min
Joyce hosts a ribbon-cutting for the birthing center; Matt and Serena take on an awkward assignment; Ron tries to knock out a quick physical before his fishing trip.
Open episode 17 ↗18. We Make Time
Air date: 2026-04-06 · 30 min
When a doctor becomes a patient, his co-workers rally around him, whether he likes it or not; Matt and Serena need to talk.
Open episode 18 ↗