Deal With It

HYPOCHONDRIAC: What starts out as simple exercises in staying healthy quickly turns into a series of obsessive procedures, as our contestant finds creative ways of keeping the germs at bay. Co-host: Howie Mandel. BEST MEDICINE: When a contestant starts acting goofy after taking a mystery pill, her brother must try and stop her from grazing on the décor, and blowing on his belly button. Co-host: Nick Cannon

ART CLASS: Beauty is only skin deep, and this contestant experiences that firsthand, after requesting that a model in an art class get nude for the sake of her sculpture. Co-host: Heidi Klum. CRIME FIGHTER: After witnessing a shady diner swipe some cash from a nearby table, our contestant dons a mask and cape, and gives the man a taste of vigilante justice by showing him the door...then throwing him through it. Co-hosts: Roman Atwood and Dennis Roady.

MEMORIAL: A devastated friend questions the morality of our contestant, after she's instructed to deface a deceased man's portrait during a memorial service. Co-host: Iliza Shlesinger. THE OTHER MAN: After instructing this contestant to reveal that he's divorcing her mother, his daughter's day can't get any worse. That is, until she meets her new step-dad. Co host: The Miz

CONVERTED: A contestant has converted to a new-age religion, and must put their rituals on display by anointing their friend with a blessing of barbeque sauce. Co-host: Gary Owen. DÉJÀ VU: A series of reoccurring events leaves this contestant in a loop, and his friend wondering whether or not she's losing her mind. Co-hosts: Kendall and Kylie Jenner.

WITNESS RELOCATION: A contestant is instructed to disguise her identity, after a run-in with a couple of mobsters reveals a clue about her mysterious past. Co-host: Chris Jericho. BEAUTY SCHOOL PICKUP: When a beautiful beautician starts flirting with our contestant, he must enlist the help of the most awkward wingman ever...his girlfriend. Co-host: Bill Engvall.

TIGER URINE: After divulging her digestive issues, this contestant reveals her questionable new dietary supplement that leaves a bad taste in her friend's mouth. Co-host: David Koechner. YOUR BIGGEST FAN: A superfan's flattery goes a little too far, when our contestant is tasked with convincing her rock star boyfriend to let the creepy stranger stay the night at his place. Co-host: Alex Mandel.

DOUBLE DATE: When our contestant reveals to her sister that she's set them both up on a blind date with two guys from the Internet, neither of their dates comes anywhere close to being "prince charming." Co-host: Chuey Martinez. EAT YOUR VEGETABLES: Bob Saget's new book "Dirty Daddy" inspires a bevy of bizarre behavior from our contestant, and when he ducks for cover, his date may just duck out the door. Co-host: Bob Saget.

CUTESY PIE: After whispering sweet nothings to his friend, our contestant is instructed to take their relationship to the next level, by locking lips with him in an unusual way. Co-host: Howie Mandel. END TIMES: The end is nigh, as this contestant must convince her friend that the world is coming to an end, then brace for impact by hiding under their table. Co-host: Kevin Nealon.

ESCORT: After dropping the news that she's an escort for older men, our contestant and her friend must deal with a creepy client, who wants to take them out for a night on the town. Co-host: Kelly Osbourne. PATRIOT: After sarcastically saluting a veteran, then swapping made-up war stories with the man, this contestant has his friend marching straight for the door. Co-host: Moshe Kasher.

TIGER URINE: a questionable new dietary supplement; YOUR BIGGEST FAN: a fan's flattery goes too far.

LAUGHS: This contestant takes the saying "laughter is the best medicine" a little too seriously, after getting the giggles at his waiter's misfortunes. Co-hosts: Bill & Giuliana Rancic. THE ACCIDENT: H20 is what's on the menu during this prank that escalates when our contestant has an accident in his pants and needs the restaurant's help to dry them. Co-host: Alex Mandel.

A contestant must sign off on bizarre online purchases; revealing a passion for the effeminate.

EMBARRASSING PARENT: After describing her scandalous bedroom behavior, a mother takes safe sex lessons a little too far in front of her mortified daughter. Co-host: Nick Cannon. EASILY HURT: A picture is worth a thousand words, unless you are the contestant's girlfriend, who has to deal with her boyfriend's clumsy attempts at communication after biting his tongue. Co-host: Howie Mandel.

FOOTBALL: This contestant has football on the brain and decides to kick off the new season while her friend watches from the sideline. Co-host: Bobby Lee. CHAMPAGNE PROBLEMS: After faking a foot injury, a contestant enlists the help of a friend, then offers a thank you with a face full of foot. Co-host: Ross Matthews.

WINE TASTING: After a contestant hijacks a wine-tasting seminar and chugs from a $3,000 bottle of wine, her friend might just want a drink of her own. Co-host: Jeannie Mai. THE WILL: A contestant's daughter is having the worst day of her life after her father informs her she's out of his will. The icing on the cake? He's letting his sexy new attorney handle the money. Co-host: Jerry O'Connell.

STAKEOUT: After witnessing the contestant confiscate a stranger's personal belongings, this friend does all he can to prevent the paranoia from resulting in someone wearing handcuffs. Co-host: Kym Whitley. BLOWOUT: When the contestant notices an elderly lady celebrating her birthday, he joins in the fun by blowing out the candles in an unusual way. Co-host: Josh Wolf.

HIGH SCHOOL SWEETHEART: A contestant takes the concept of mid-life crisis to a whole new level as she is tasked with introducing her friend to Kevin, her high school sweetheart. Co-host: King Bach. DOCTOR'S WAITING ROOM: After irritating several patients in a doctor's waiting room, a contestant has to deal with her husband's rising blood pressure. Co-host: Alex Mandel.

TURKEY DANCE: After demanding some turkey, then stealing two of the raw birds from a nearby counter, a contestant has his hands full trying to explain himself to his irritated wife. Co-host: Howie Mandel. THANKSGIVING: A contestant gets too caught up in the Thanksgiving spirit when she drinks straight from a gravy boat, leaving her sister anything but thankful for her bizarre behavior. Co-host: Jack Osbourne.

SPEED DATING (HALLMARK): After stumbling into a speed dating session, a contestant's girlfriend is in for the worst date of her life when an attractive woman wants to "lock-in" with her man. Co-host: Jessimae Peluso. CUPCAKES: Our contestant is unhappy with a cupcake focus group, and after being told not to eat any of the cupcakes, he decides to bite off more than he can chew, literally. Co-host: Penn Jillette.

NARCOLEPTIC: A contestant can't stay awake, and when slapping herself and splashing water on her face doesn't work, she has to get her friend to give her a rude awakening. Co-host: Chuey Martinez. YOGA CLASS: A contestant is tasked with disrupting a yoga class by demonstrating his obnoxious custom stretches. Co-host: Josh Meyers.